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Filtered Search Results
Medchemexpress LLC HY-B0494 100mg Medchemexpress, Bufexamac CAS:2438-72-4 Purity:>98%
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Medchemexpress, HY-B0494 100mg Bufexamac CAS:2438-72-4 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem 4-Ethyl-1 2-dimethoxybenzene | ≥97% | CAS 5888-51-7 | C10H14O2 | 250mg
4-Ethyl-1 2-dimethoxybenzene | ≥97% | CAS 5888-51-7 | C10H14O2 | 250mg
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Aobchem 1-Iodo-2 3-dimethoxybenzene | ≥95% | CAS 25245-33-4 | C8H9IO2 | 500mg
1-Iodo-2 3-dimethoxybenzene | ≥95% | CAS 25245-33-4 | C8H9IO2 | 500mg
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Aobchem 4-Bromo-1 2-diethoxybenzene | ≥95% | CAS 53207-08-2 | C10H13BrO2 | 250mg
4-Bromo-1 2-diethoxybenzene | ≥95% | CAS 53207-08-2 | C10H13BrO2 | 250mg
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Medchemexpress LLC HY-18603 5mg Medchemexpress, FIIN-3 CAS:1637735-84-2 Purity:>98%
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Medchemexpress, HY-18603 5mg FIIN-3 CAS:1637735-84-2 FIIN-3 is an irreversible inhibitor of FGFR with an IC50 of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.52% | 511.03 | 100 MG
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JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
- Inhibitor of JAK.
- Inhibits STAT6 phosphorylation by 60% in IL-13-induced lung tissue in a mouse model of pSTAT6 induction (oral aspirate, 0.5 mg/mL, 50 μL).
- Inhibits 88% of BALF eosinophils in a male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung (oral aspirate, 0.1-1.0 mg/mL, 50 μL).
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Aobchem 6-Phenoxy- -phenyl-3-pyridinemethanol | 95% | CAS 1355195-57-1 | C18H15NO2 | 500mg
6-Phenoxy- -phenyl-3-pyridinemethanol | 95% | CAS 1355195-57-1 | C18H15NO2 | 500mg
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Medchemexpress LLC Benzamide, 2,6-dichloro-n-[3-(1h-indol-5-yl)-1h-indazol-5-yl]- | 2249801-12-3 | 98.2% | 50 MG
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MD2-TLR4-IN-1 is an antagonist of the myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex. It inhibits Lipopolysaccharides (LPS)-induced expression of TNF-α and IL-6 in macrophages. This compound supports research into acute lung injury (ALI) and exhibits anti-inflammatory activity.
- Inhibits NF-κB in RAW264.7 macrophages.
- Directly binds to and disrupts MD2-TLR4 complex activation.
- Suppresses NF-κB p65 subunit nuclear levels in LPS-induced macrophages.
- Reduces macrophage infiltration and improves lung tissue histopathology in LPS-challenged mice.
- Decreases airspace inflammation and LPS-induced myeloperoxidase (MPO) activity.
- Lowers LPS-induced serum TNF-α levels and inflammatory mRNA levels in lung tissues.
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Medchemexpress LLC (3-aminopropyl)(n-butyl)phosphinic acid | 123690-78-8 | 98.0% | 50 MG
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CGP 36742 (SGS-742) is an orally active, blood-brain barrier-penetrant, selective GABAB receptor antagonist (reported IC50 ≈ 36 μM) supplied as a research-grade compound for in vitro and in vivo neuroscience studies, including depression and cognition research.
- Selective GABAB receptor antagonist with reported IC50 ≈ 36 μM.
- Penetrates the blood-brain barrier, suitable for CNS pharmacology studies.
- Provided as a solid research reagent in small milligram pack sizes.
- Commonly used in behavioral pharmacology and receptor binding studies related to depression and cognition.
- Reported purity typically around 98.0%, varying by supplier and lot.
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Medchemexpress LLC AS2717638 50mg | 2148339-28-8 | 50 MG
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AS-2717638 is a selective, brain-penetrant, orally active lysophosphatidic acid receptor 5 (LPA5) antagonist used in pharmacology and neuroscience research to probe LPA5-mediated signaling and pain models.
- Selective LPA5 antagonist (IC50 = 0.038 μM) for receptor pharmacology studies.
- Brain-penetrant and orally active for in vivo models.
- High purity suitable for biological assays.
- Stable when stored at -20°C with a long shelf life.
- Available in small-scale quantities for preclinical research.
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Medchemexpress LLC 1-cyclobutyl-3-(2,6-dimethylphenyl)-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2(1H)-one (methoxy-piperazinyl substituted) | 2172617-15-9 | 99.8% | 5 MG
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YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor for research use. It inhibits SIK1, SIK2, and SIK3 with IC50 values of 6.56 nM, 1.77 nM, and 20.5 nM, respectively. The compound is supplied as a high-purity solid with good DMSO solubility for biochemical and cellular studies.
- Potent inhibition of SIK1, SIK2, and SIK3 at low-nanomolar concentrations.
- High purity suitable for research applications.
- Soluble in DMSO at 16.67 mg/mL (31.59 mM).
- Solid storage recommended at -20°C; in solution store at -80°C for long-term stability.
- Available in small research sizes for assay development.
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Aobchem 4-Phenoxy-2-(trifluoromethyl)phenylboronic acid pinacol ester | ≥97% | CAS 1196396-64-1 | C19H20BF3O3 | 1g
4-Phenoxy-2-(trifluoromethyl)phenylboronic acid pinacol ester | ≥97% | CAS 1196396-64-1 | C19H20BF3O3 | 1g
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eMolecules 2070014-90-1 | Medchem Express | LY 303511 (hydrochloride) | 5mg | 446266224 | HY-15643A | MFCD28167798 | 342.82 | C19H19ClN2O2
Ambeed | Bis(pyridin-3-yl)-4H-124-triazol-4-amine | 250mg | 600849500 | A888270 | 38629-66-2 | MFCD02187295 | 238.254 | C12H10N6
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eMolecules 1262414-04-9 | Medchem Express | Cenerimod | 5mg | 446268733 | HY-17606 | MFCD30530772 | 453.539 | C25H31N3O5
Medchem Express | Deflazacort | 50mg | 446263206 | HY-13609 | 14484-47-0 | MFCD00866106 | 441.524 | C25H31NO6
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eMolecules 93-40-3 | 3,4-Dimethoxyphenylacetic acid | Ambeed | MFCD00004335 | 196.202 | C10H12O4 | 98.000 | COc1ccc(CC(O)=O)cc1OC | 5g | 490503044
3,4-Dimethoxyphenylacetic acid | Ambeed | 93-40-3 | MFCD00004335 | 196.202 | C10H12O4 | 98.000 | COc1ccc(CC(O)=O)cc1OC | 5g | 490503044
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